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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1956 1
1964 2
1965 1
1966 1
1967 4
1968 1
1969 5
1970 1
1971 6
1972 5
1973 2
1974 5
1975 17
1976 19
1977 19
1978 18
1979 24
1980 23
1981 25
1982 34
1983 31
1984 48
1985 49
1986 72
1987 104
1988 114
1989 198
1990 257
1991 315
1992 344
1993 435
1994 449
1995 599
1996 548
1997 669
1998 681
1999 736
2000 816
2001 832
2002 839
2003 796
2004 909
2005 878
2006 859
2007 886
2008 904
2009 953
2010 935
2011 885
2012 908
2013 897
2014 898
2015 918
2016 861
2017 830
2018 743
2019 801
2020 867
2021 911
2022 842
2023 763
2024 343

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25,025 results

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Page 1
Preface. Catalytic RNA.
Soukup GA. Soukup GA. Prog Mol Biol Transl Sci. 2013;120:xi. doi: 10.1016/B978-0-12-381286-5.09987-X. Prog Mol Biol Transl Sci. 2013. PMID: 24156946 No abstract available.
Self-cleaving catalytic RNA.
Long DM, Uhlenbeck OC. Long DM, et al. FASEB J. 1993 Jan;7(1):25-30. doi: 10.1096/fasebj.7.1.8422971. FASEB J. 1993. PMID: 8422971 Review.
We describe the structures and catalytic properties of several naturally occurring self-cleaving RNA motifs that give 2', 3' cyclic phosphate products. ...The role of divalent cations in the catalytic mechanism is discussed....
We describe the structures and catalytic properties of several naturally occurring self-cleaving RNA motifs that give 2', 3' c …
Catalytic RNA: structure and mechanism.
Cech TR. Cech TR. Biochem Soc Trans. 1993 May;21(2):229-34. doi: 10.1042/bst0210229. Biochem Soc Trans. 1993. PMID: 8359471 Review. No abstract available.
Catalytic promiscuity in the RNA World may have aided the evolution of prebiotic metabolism.
Vörös D, Könnyű B, Czárán T. Vörös D, et al. PLoS Comput Biol. 2021 Jan 26;17(1):e1008634. doi: 10.1371/journal.pcbi.1008634. eCollection 2021 Jan. PLoS Comput Biol. 2021. PMID: 33497378 Free PMC article.
The complexity of the MCRS chemical engine can be increased by assuming that each replicator species may catalyse more than a single reaction of metabolism, with different catalytic activities of the same RNA sequence being in a trade-off relation: one catalytic …
The complexity of the MCRS chemical engine can be increased by assuming that each replicator species may catalyse more than a single reactio …
In vitro selection and evolution of RNA: applications for catalytic RNA, molecular recognition, and drug discovery.
Burke JM, Berzal-Herranz A. Burke JM, et al. FASEB J. 1993 Jan;7(1):106-12. doi: 10.1096/fasebj.7.1.8422956. FASEB J. 1993. PMID: 8422956 Review.
Selection in the absence of living cells is possible because some RNA molecules possess a selectable "phenotype" (catalytic activity or ligand binding) as well as a "genotype" (nucleotide sequence). This review discusses the basic principles of in vitro selection te …
Selection in the absence of living cells is possible because some RNA molecules possess a selectable "phenotype" (catalytic ac …
Ligand-dependent ribozymes.
Felletti M, Hartig JS. Felletti M, et al. Wiley Interdiscip Rev RNA. 2017 Mar;8(2). doi: 10.1002/wrna.1395. Epub 2016 Sep 30. Wiley Interdiscip Rev RNA. 2017. PMID: 27687155 Review.
The discovery of catalytic RNA (ribozymes) more than 30 years ago significantly widened the horizon of RNA-based functions in natural systems. ...We summarize the occurrence of ligand-dependent ribozymes in nature and the many examples realized by researchers …
The discovery of catalytic RNA (ribozymes) more than 30 years ago significantly widened the horizon of RNA-based functi …
Catalytic RNA nano-objects formed by self-assembly of group I ribozyme dimers serving as unit structures.
Kiyooka R, Akagi J, Hidaka K, Sugiyama H, Endo M, Matsumura S, Ikawa Y. Kiyooka R, et al. J Biosci Bioeng. 2020 Sep;130(3):253-259. doi: 10.1016/j.jbiosc.2020.04.010. Epub 2020 May 22. J Biosci Bioeng. 2020. PMID: 32451246
Ribozymes with modular structures are attractive platforms for the construction of nanoscale RNA objects with biological functions. We designed group I ribozyme dimers as unit ribozyme dimers (Urds), which self-assembled to form their polymeric states and also oligomeric s …
Ribozymes with modular structures are attractive platforms for the construction of nanoscale RNA objects with biological functions. W …
Recent insights on RNA folding mechanisms from catalytic RNA.
Woodson SA. Woodson SA. Cell Mol Life Sci. 2000 May;57(5):796-808. doi: 10.1007/s000180050042. Cell Mol Life Sci. 2000. PMID: 10892344 Review.
Methods for probing RNA structure in real time have revealed that initial folding steps are complete in less than a second. Refolding of large catalytic RNAs in vitro often results in long-lived intermediates that reach the native structure very slowly. ...
Methods for probing RNA structure in real time have revealed that initial folding steps are complete in less than a second. Refolding …
Structural dynamics of catalytic RNA highlighted by fluorescence resonance energy transfer.
Walter NG. Walter NG. Methods. 2001 Sep;25(1):19-30. doi: 10.1006/meth.2001.1212. Methods. 2001. PMID: 11558994 Review.
The reason probably is twofold: (a) Life started as a prebiotic RNA World, in which RNA served as the genetic information carrier and catalyzed all chemical reactions required for its proliferation and (b) some of the RNA World functions were conserved throug …
The reason probably is twofold: (a) Life started as a prebiotic RNA World, in which RNA served as the genetic information carr …
The many faces of the hairpin ribozyme: structural and functional variants of a small catalytic RNA.
Müller S, Appel B, Krellenberg T, Petkovic S. Müller S, et al. IUBMB Life. 2012 Jan;64(1):36-47. doi: 10.1002/iub.575. Epub 2011 Nov 30. IUBMB Life. 2012. PMID: 22131309 Free article. Review.
The hairpin ribozyme is a small catalytic RNA that has been reengineered resulting in a number of variants with extended or even new functions. ...Furthermore, several hairpin ribozyme variants have been engineered for knock down of specific RNA substrates by …
The hairpin ribozyme is a small catalytic RNA that has been reengineered resulting in a number of variants with extended or ev …
25,025 results
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